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- Martyr Sabbas 1 May
- Venerable Saints Sabbas and Alexis the Hermit, of the Kiev Caves (13th century) 24 April
- Saint Sabbas II, Archbishop of Serbia (1271) 8 February
- New Martyr Sabbas Nigdelis the Samoladan, beheaded at Koutzouk-Karamani, Constantinople, buried in Eğri Kapı ("Crooked Gate") (1726) 12 November
- Venerable Sabbas of Ioannina (15th century) 3 February
- Venerable Sabbas of Moscow, Abbot (1410) 13 June
- Venerable Sabbas of Moscow, Monk of Andronikov Monastery, Moscow (1378) 16 June
- Venerable Sabbas of Storozhev, Abbot of Storozhev in Zvenigorod, Disciple of Venerable Sergius of Radonezh (1406) 3 December
- Martyr Sabbas Stratelates 29 October
- Martyr Sabbas Stratelates ("the General") of Rome, and 70 soldiers with him (272) 24 April
- Venerable Sabbas the Fool-for-Christ, of Vatopedi monastery, Mount Athos (1350) 15 June
- Saint Sabbas the Fool-for-Christ, of Vatopedi monastery, Mount Athos (1350) 5 October
- Martyr Sabbas the Goth (Sabbas Stratelates), at Buzau in Wallachia (372) 18 April
- Martyr Sabbas the Goth, at Buzău in Wallachia (372) 12 April, 15 April
- Venerable Sabbas the New of Sicily, Abbot (995) 5 February
- Saint Sabbas the Sanctified (532) 5 December
- Venerable Sabbas, abbot of Vishera in Novgorod, the Wonderworker (1460) 1 October
- Saint Sabbas, Archbishop of Sourozh, Crimea (11th century) 2 April
- Saint Sabbas, Bishop of Dafnousia 2 May
- Saint Sabbas, founder and Abbot of Krypetsk Monastery (Pskov) (1495) 28 August
- Saint Sabbas, monk, of Benephali 27 August
- Venerable Sabbatius, monk of Tver (1434), and his disciple St. Euphrosynus (1460) 2 March
- Venerable Sabbatius, Wonderworker of Solovki (1435) 27 September
- Venerable Sabiana, Abbess of Samtskhe Convent (11th century) 31 December
- Saint Sabina of Troyes, by tradition the sister of St Sabinian of Troyes in France where she was venerated together with him (c. 275) West, before the Schism 29 August
- Saint Sabina, matron and martyr from Rome (c. 126) West, before the Schism 29 August
- Hieromartyrs Sabinian and Potentian (c. 303) West, before the Schism 31 December
- Martyr Sabinian of Troyes (275) West, before the Schism 29 January
- Saint Sabinian, Third Abbot of Moutier-Saint-Chaffre in France (c. 720) West, before the Schism 22 November
- Saint Sabinus (Savinus) and Cyprian, two martyrs and brothers venerated in Brescia in Italy West, before the Schism 11 July
- Saint Sabinus of Canosa, Bishop of Canosa in Apulia in Italy and Confessor, and a friend of St Benedict (c. 566) West, before the Schism 9 February
- Martyr Sabinus of Hermopolis, Egypt (287) 16 March
- Saint Sabinus of Piacenza, Bishop of Piacenza in Italy and a close friend of Saint Ambrose, renowned for miracles (420) West, before the Schism 11 December
- Martyrs Sabinus of Spoleto, Exuperantius, Marcellus, Venustian and Companions (303) West, before the Schism 30 December
- Venerable Sabinus, a bishop who became a monastic 15 September
- Saint Sabinus, a saint venerated near Poitiers in France, said to have been a disciple of St Germanus of Auxerre, confessor (5th century) West, before the Schism 11 July
- Saint Sabinus, Archbishop of Cyprus (successor of St. Epiphanius to the Cypriot cathedra) (5th century) 12 May
- Saint Sabinus, Bishop of Catania, Wonderworker (760) 15 October
- Martyr Sabinus, by fire 25 October
- Saint Sacer (Mo-Sacra, Mosacra), founder of the monastery of Saggart near Dublin in Ireland (7th century) West, before the Schism 3 March
- Saint Sacerdos of Limoges, Bishop of Limoges (720) West, before the Schism 4 May
- Saint Sacerdos of Lyon, Bishop of Lyon in Gaul (551) West, before the Schism 12 September
- Saint Sacerdos of Saguntum (c. 560) West, before the Schism 5 May
- Saint Sadalberga, foundress of the convent of St. John the Baptist at Laon (c. 665) West, before the Schism 22 September
- Hieromartyr Sadoc (Sadoth), Bishop of Persia, and 120 martyrs with him (342) 19 October
- Hieromartyr Sadoc of Persia (Sadoth), Bishop of Persia, and 128 Martyrs with him (343) 20 February
- Saint Sadwrn (Sadwen), hermit, brother of St Illtyd and disciple of St Cadfan (6th century) West, before the Schism 29 November
- Saint Sæbbi of Essex (Sebbi, Sebba), King of Essex and monk (c. 694) West, before the Schism 29 August
- Saint Sæthryth (Sethrid), Abbess (c. 660) West, before the Schism 10 January
- Saint-Righteous Hademunda, Margravine of Ebersberg, pilgrim (1029) West, before the Schism 11 November
- Martyr Sais 5 January
- Martyr Sak (Saktus, Sanctus) the Persian 17 November
- Venerable Salamanes the Silent (Salamanes the Hesychast) of the Euphrates (c. 400) 23 January
- Saint Sallustian of Sardinia, confessor West, before the Schism 8 June
- Saints Salome and Judith, anchoresses at Oberalteich Abbey (dedicated to Saints Peter and Paul), in Germany (9th century) West, before the Schism 29 June
- Martyr Salome of Jerusalem and Kartli, who suffered under the Persians (13th century) 20 July
- Saints Salome of Ujarma and Perozhavra of Sivnia, Georgia (c. 361) 15 January
- Saint Salomon of Cornwall, by tradition born in Cornwall, the husband of St Gwen and father of St Cuby (Cybi), he lived in Brittany and was murdered by heathen (5th century) West, before the Schism 25 June
- Martyr Salonas the Roman, by the sword 23 May
- Saint Salumptinus, a Bishop of Jerusalem 24 July
- Saint Salvinus, Bishop of Verona in Italy (562) West, before the Schism 12 October
- Saint Salvinus, third Bishop of Verdun in the north of France (c. 420) West, before the Schism 4 September
- Saint Salvius (Saire), a hermit in France who lived at the place now called Saint-Saire after him (6th century) West, before the Schism 28 October
- Saint Salvius (Sauve), Bishop of Amiens, his relics were enshrined in Montreuil in Picardy (c. 625) West, before the Schism 12 January
- Saints Salvius and Superius (c. 768) West, before the Schism 26 June
- Saint Salvius, Abbot of Albelda in the north of Spain (962) West, before the Schism 10 February
- Saint Salvius, Bishop of Albi in Gaul, Confessor (584) West, before the Schism 10 September
- Martyr Salvius, in North Africa, eulogized by Saint Augustine West, before the Schism 11 January
- Venerable Sampson the Hospitable of Constantinople (530) 27 June
- Saint Samson of Dol, Bishop of Dol, in Brittany (c. 565) West, before the Schism 28 July
- Saint Samthann, foundress of the convent of Clonbroney in Co. Longford in Ireland (6th century) West, before the Schism 18 December
- Prophet Samuel (11th century BC) 20 August
- Saint Samuel of Edessa, presbyter (5-6th century) 9 August
- Saint Sanctan, Bishop of Kill-da-Les and Kill-na-Sanctan near Dublin in Ireland (6th century) West, before the Schism 9 May
- Saint Sanctinus, by tradition the first Bishop of Meaux and a disciple of St Denis of Paris (c. 300) West, before the Schism 22 September
- Martyr Sanctius (Sancho, Sancius), soldier, at Córdoba (851) West, before the Schism 5 June
- Saint Sandalus (Sandila, Sandolus, Sandulf), a martyr in Cordoba in Spain under the Moors (c. 855) West, before the Schism 3 September
- Saint Sandratus (Sandradus), Abbot of Gladbach, and in 981 Abbot of Weissenburg (986) West, before the Schism 24 August
- Virgin-martyr Sandukht [Sagdukht] (c. 50) 5 May
- Saint Sarah the Righteous (17th century BC) 19 August
- Venerable Sarapion of Cyprus 7 February
- Martyrs Sarbel and his sister Barbe (Thathuil, Thiphael; Bebaia, Thivea) of Edessa (98-138) 5 September
- Martyr Sarbellus (Sarvillos, Zarvilos), by stoning 4 September
- Martyrs Sarbelus (Thathuil) and his sister Bebaia, of Edessa (110) 29 January, 15 October
- Martyr Sarbelus of Edessa (98-138) 5 September
- Venerable Sarmata of "The Paradise", ascetic of the desert, Egypt (c. 362) 30 August
- Saint Sarmean, Catholicos of Kartli, Georgia (774) 21 August
- Saint Saturnina, a virgin-martyr from Germany murdered near Arras in France West, before the Schism 4 June
- Saint Saturninus and Companions, a group of ten martyrs in North Africa West, before the Schism 22 March
- Hieromartyrs Saturninus and Sisinius (c. 309) West, before the Schism 29 November
- Saint Saturninus of Cagliari, a martyr in Cagliari in Sardinia under Diocletian, beheaded during a pagan festival of Jupiter (303) West, before the Schism 30 October
- Saint Saturninus, Bishop of Verona and Confessor (4th century) West, before the Schism 7 April
- Martyrs Saturninus, Castulus, Magnus and Lucius, who belonged to the flock of St Valentine, Bishop of Terni in Italy (273) West, before the Schism 15 February
- Martyrs Saturninus, Dativus, Felix, Ampelius, Victoria and Companions (304) West, before the Schism 11 February
- Martyrs Saturninus, Thyrsus and Victor, at Alexandria 31 January
- Hieromartyr Saturninus, venerated as the first Bishop of Toulouse (c. 257) West, before the Schism 29 November
- Saint Satyrus of Milan, elder brother of St Ambrose of Milan in Italy (376) West, before the Schism 17 September
- New Hieromartyrs Sava (Trlajic), Bishop of Gornji Karlovac (1941) and Đorđe Bogić, Priest, of Nasice 4 July
- Saint Sava I (Savva I), Enlightener and first Archbishop of Serbia (1235) 14 January
- Saint Sava I, Enlightener and first Archbishop of Serbia (1235 or 1237) 12 January
- Saint Sava III, Archbishop of Serbia (1316) 26 July
- Saint Savin (Sabinus), venerated as one of the Apostles of the Lavedan, in the Pyrenees, France (c. 820) West, before the Schism 9 October
- Saint Savina of Milan (Sabina), born in Milan, she ministered to martyrs in prison and buried their bodies during the persecution of Diocletian (311) West, before the Schism 30 January
- Venerable new martyr Savvas of Stagira (Savvas Stageiritis) (1821) 10 June
- Venerable Savvas the New of Kalymnos (1947) 24 March, 25 March, 7 April
- Saint Sawyl Penuchel, the father of Asaph of Wales (6th century) West, before the Schism 15 January
- Saint Scannal of Cell-Coleraine in Ireland, a disciple of Saint Columba (563) West, before the Schism 3 May
- Schema-abbess Juliana (1393) and Schema-nun Eupraxia (1394), of the Monastery of the Conception in Moscow 3 May
- Venerable Schema-Abbess Magdalena (Dosmanova) of New Tikhvin Convent in Siberia (1934) 16 July
- Schema-Igumen Ioann (Alexeev) of New Valamo Monastery (1958) 5 June
- Venerable Schemamonk Agapitus the Blind, of Valaam Monastery (1905) 7 April
- Venerable Schemamonk Cyril and Schemanun Maria (both c. 1337), parents of Saint Sergius of Radonezh 18 January
- Schemamonk Luke of Glinsk Hermitage (1898) 1 May
- Martyr Schinon (Skinus), by the sword 23 December
- Saint Scholastica of Italy, sister of St. Benedict of Nursia (543) West, before the Schism 10 February
- Saint Schotin (Scarthin), a disciple of Saint David in Wales, lived as a hermit on Mt Mairge in Leix (County Laois) for many years (6th century) West, before the Schism 6 January
- Saint Schottin (Schotin, Scarthin), hermit of Kilkenny, Ireland (6th century) West, before the Schism 2 January
- Saint Seachnall (Sechnall), first Bishop of Dunsauglin in Meath in Ireland and later served in Armagh (457) West, before the Schism 27 November
- Saint Seaxburh of Ely (Saxburgh, Sexburga), foundress of the abbey at Minster-in-Sheppey and later Abbess of Ely (699) West, before the Schism 6 July
- Saint Sebaldus, probably born in England, he lived as a hermit near Vicenza in Italy, then preached with St Willibald in the Reichswald in Germany (c. 770) West, before the Schism 19 August
- Venerable Sebastian of Poshekhonye, founder of Sokhotsk Monastery, Yaroslavl (1500) 26 February
- Venerable Sebastian the Confessor of Optina and Karaganda (Elder Sebastian of Optina), Wonderworker and Clairvoyant, last of the great Optina Elders (1966) 19 April
- Saint Sebastian, a monk who became Archbishop of Esztergom in 1002 and Primate of Hungary in the time of Saint Stephen I of Hungary (c. 1036) West, before the Schism 30 December
- Venerable Sebastian, Abbot of Poshekhonye Monastery, Vologda (1500) 18 December
- Martyr Sebastian, at Rome, and his companions West, before the Schism 18 December
- Saint Sebastian, one of the most renowned of all the martyrs of Rome (c. 288) West, before the Schism 20 January
- Virgin-martyr Sebastiana Ageyev-Zueva (1938) 28 June
- Saint Sebastiana, disciple of Apostle Paul, martyred at Heraclea (86) 16 September
- Martyr Sebastiani (1st century) 24 October
- Saint Sebastiani the Wonderworker 7 June
- Saint Secundellus the Deacon, in Gaul (6th century) West, before the Schism 29 April
- Saints Secundian, Marcellian and Verian, martyrs who suffered near Civitavecchia in Italy under Decius (250) West, before the Schism 9 August
- Virgin Martyr Secundina, scourged to death near Rome in the persecution of Decius (c. 250) West, before the Schism 15 January
- Saints Secundinus, Agrippinus, Maximus, Fortunatus and Martialis, martyrs in Pannonia (4th century) West, before the Schism 15 July
- Martyr Secundinus, in Cordoba in Spain under Diocletian (c. 306) West, before the Schism 21 May
- Hieromartyr Secundus and those with him, in Alexandria (356) 21 May
- Martyr Secundus of Asti, a noble from Asti in Piedmont in Italy and an officer in the imperial army, beheaded in Asti under Hadrian (119) West, before the Schism 29 March
- Saint Secundus, a soldier of the Theban Legion martyred near Ventimiglia in Italy (3rd century) West, before the Schism 26 August
- Martyr Secundus, an Enlightener of Spain, sent by the Apostles to Spain to preach the Gospel of Jesus Christ (1st century) 28 December
- Martyr Secundus, at Amelia in Umbria, when thrown into the Tiber (304) West, before the Schism 1 June
- Saint Sedna (Sétna, Sidonius), Bishop of Ossory in Ireland and a friend of St Luanus (c. 570) West, before the Schism 10 March
- Saint Seguanos (Sequanus, Seine, Sigo), in the diocese of Langres in Gaul, Confessor (580) West, before the Schism 19 September
- Saint Seigine (Ségéne mac Fiachnaí), Abbot of Iona (652) West, before the Schism 12 August
- Saint Seiriol the Righteous, Abbott of Penmon Priory, brother of King Cynlas of Rhos and King Einion of Llŷn (6th century) West, before the Schism 2 January
- Saint Seiriol, Abbot of Penmon Priory, Anglesey (6th century) West, before the Schism 1 February
- Martyr Seleucius (Selefkos), by sawing in two 23 May
- Martyrs Seleucius and Stratonica his wife, myrrh-gushers 31 October
- Martyr Seleucus of Galatia (320) 13 September
- Saint Selyf (Selyr, Levan), a hermit in St Levan in Cornwall (6th century) West, before the Schism 25 June
- Saint Senach (Snach), a disciple of St Finian and his successor as Abbot of Clonard in Ireland (6th century) West, before the Schism 3 August
- Saint Senán mac Geirrcinn (Senames), a monk in Kilmanagh in Ireland (c. 540) West, before the Schism 8 March
- Saint Senan of North Wales, hermit (7th century) West, before the Schism 29 April
- Saint Senator of Milan, Bishop of Milan (480) West, before the Schism 28 May
- Saint Senator, a saint honoured in Albano in Italy West, before the Schism 26 September
- The Holy Senators of Sebasteia, martyrs of senatorial rank, martyred under Licinius, by fire (c. 315) 2 November
- Venerable Sennouphios the Standard-bearer, of Latomos Monastery in Thessalonica (9th century) 25 March
- Saint Sennuphius the Standard-bearer, of Egypt (late 4th century) 28 June
- Saint Senoch the Healer, Abbot, of Tours, Gaul (576) West, before the Schism 24 October
- Saint Senorina, a Galician abbess who served as the abbess of the Benedictine convent of St John of Venaria (Vieyra) (982) West, before the Schism 22 April
- Venerable Serafim (Popescu) the Long-Suffering of Sâmbăta de Sus, Archimandrite (1990) 20 December
- Saint Seraphim (Amelin), schema-archimandrite of Glinsk Hermitage (1958) 5 October
- New Hieromartyrs Seraphim (Bogoslovsky) and Theognostus (Pivovarov), Hieromonks of a skete at Kyzyl-Zharskoe, Kazakhstan (1921) 29 July
- New Hieromartyr Seraphim (Shakhmut), Archimandrite, of Grodno (Belarus) (1946) 24 August
- Saint Seraphim (Sobolev), Archbishop of Bogucharsk and Wonderworker of Sofia (1950) 13 February
- Saint Seraphim (Zenobius), Schema-Metropolitan of Tetritskaro, Georgia, monk of Glinsk Monastery (1985) 23 February
- New Hieromartyr Seraphim (Zvezdinsky), Bishop of Dmitrov (1937) 13 August
- New Hieromartyr Seraphim Bulashov, Abbot of Holy Transfiguration Guslitsky Monastery , Moscow (1938) 23 January
- New Hieromartyr Seraphim Chichagov, Metropolitan of St. Petersburg (1937) 28 November
- Saint Seraphim of Mt. Dombos of Livadeia (1602) 6 May
- Venerable Seraphim of Vyritsa (1949) 21 March
- New Hieromartyr Seraphim Ostroumov, Archbishop of Smolensk (1937) 25 November
- Saint Seraphim Romantsov, Schema-Archimandrite of Sukhumi, Abkhazia, Elder of Glinsk Monastery (1976) 19 December
- New Hieromartyr Seraphim Samoilovich, Archbishop of Uglich (1937) 4 November
- New Hieromartyr Seraphim Schelokov (1937) 8 October
- New Hieromartyr Seraphim Thievart, Hieromonk of Moscow (1931) 23 November
- New Hieromartyr Seraphim, Archbishop of Phanarion and Neochorion (1601) 4 December
- New Hieromartyr Seraphim, Bishop of Phanarion and Neokhorion (1601) 27 April
- New Hieromartyrs Seraphim, Theognostus, and others of Alma-Ata (1921) 16 July
- Virgin-martyr Seraphima (Serapia) of Antioch (c. 117-138) 29 July
- New Martyr Seraphima (Sulimova), Abbess of the Therapontov Convent (1918) 2 September
- Saint Serapion (Sysoev), Metropolitan of Krutitsa (1653) 2 May
- Venerable Serapion of Kozhaezersk Monastery (1611) (see also: October 19 ) 27 June
- Venerable Serapion of Kozheozersky Monastery (1611) 19 October
- Saint Serapion of Novgorod, Archbishop of Novgorod (1516) 16 March
- Venerable Serapion of Spaso-Eleazar Monastery in Pskov (1480) 7 September
- Blessed Serapion of Vladimir, Bishop of Vladimir (1275) 12 July
- Saint Serapion of Zarzma monastery, Georgia (900) 29 October
- Martyr Serapion the New, at Alexandria (194-211) 12 July
- Venerable Serapion the Sindonite, monk of Egypt (5th century) 21 March, 14 May
- Saint Serapion the Sindonite, monk, of Egypt (5th century) 7 April
- Venerable Serapion the Wonderworker, abbot of the Monastery of St. John the Baptist at David Gareja monastery complex, Georgia (1774) 24 August
- Venerable Serapion the Wonderworker, of Izborsk, Igumen (16th century) 12 June
- Saint Serapion, Bishop of Thmuis, Egypt (c. 358) 21 March
- Martyrs Serapion, Cronides (Hieronides), and Leontius, of Alexandria (237) 11 September
- Martyrs Serapion, Cronides, and Leontius, of Alexandria (c. 237) 13 September
- Saint Serapion, monk of Spaso-Eleazar Monastery, Pskov (1481) 8 September
- Martyr Serapion, under Severus (c. 205) 13 July
- Saints Serenicus and Serenus, two brothers who became monks and later settled as hermits near the River Sarthe in France (c. 669) West, before the Schism 7 May
- Saint Serenus the Gardener, martyr (307) West, before the Schism 23 February
- Saint Serenus, Bishop of Marseilles in France (606) West, before the Schism 9 August
- Saint Serf (Servanus), the Apostle of West Fife in East Scotland, who reposed and was buried in Culross (c. 583) West, before the Schism 1 July
- New Hieromartyr Sergei Uvitsky, Priest (1932) 27 February
- New Hieromartyr Sergius (Bukashkin), Hieromonk, of Novo-Alexandrovka, Moscow (1938) 23 February
- New Hieromartyr Sergius (Chernukhin), Abbot, of Danilov Monastery, Moscow (1942) 27 October
- New Hieromartyr Sergius (Druzhinin), Bishop of Narva (1937) 4 September
- Saint Sergius (George) the Confessor of Constantinople, with his wife Irene and children (c. 829-842) 13 May
- New Martyr Sergius (Trofimov) of Nizhni-Novgorod and companion (1918) 14 April
- New Hieromartyr Sergius (Zavarin), Archpriest, of Yaroslavl (1938) 1 April
- New Hieromartyr Sergius (Zverev), Archbishop of Elets and Melitopol (1937) 1 November
- Martyrs Sergius and Bacchus, in Syria (290-303) 7 October
- Saints Sergius and Barbara of Oyatsk, monastics, parents of St. Alexander of Svir (1477-1480) 15 June
- Saints Sergius and Herman, founders and abbots of Valaam Monastery, Wonderworkers (c. 1353) 28 June
- Venerable Saints Sergius and Stephen, peacefully 12 August
- Martyr Sergius Archangelskiy (1938) 24 April
- New Hieromartyr Sergius Astakhov, Deacon (1942) 18 December
- Martyr Sergius Borodavkin (1938) 23 February
- New Hieromartyrs Sergius Bukashkin and Antipas Kirillov, Hieromonks (1938) 22 February
- New Hieromartyrs Sergius Fenomenov, Basil Kolmikov, Philip Shatsky, and Vladimir Dmitrievsky, Priests (1918) 3 September
- New Hieromartyr Sergius Florinsky, Priest of Rakvere, Estonia (1918) 17 December, 30 December
- New Hieromartyr Sergius Galkovsky, Hieromonk (1917) 7 December
- New Hieromartyrs Sergius Goloshapov, Michael Uspensky and Sergius Uspensky, Priests (1937) 7 December
- Saint Sergius II, Ecumenical Patriarch of Constantinople (1019) 12 April
- New Hieromartyr Sergius Kochurov, Priest (1941) 29 November
- New Hieromartyr Sergius Konstantinov, Priest (1941) 14 November
- New Hieromartyr Sergius Lavrov, Priest (1934) 5 January
- New Hieromartyr Sergius Losev, Priest (1942) 16 September
- New Hieromartyr Sergius Mechev, Archpriest of Moscow (1941–1942) 24 December
- New Hieromartyr Sergius Mechev, Priest of Moscow (1941) 9 December
- New Hieromartyrs Sergius Mikhaev, Michael Dmitriev, Alexander Mishutin, John Malinovsky, Constantine Mikhailovsy, Alexander Serebrov, Ignatius Teslin, John... (1937) 19 November
- Venerable Sergius of Nurma in Vologda, Abbot (1412), disciple of St. Sergius of Radonezh 7 October
- Saint Sergius of Shukhtov (Shukhtom), monk (1609) 19 May
- New Hieromartyr Sergius Orlov (1937) 8 December
- New Hieromartyr Sergius Pokrovsky, Priest (1937) 19 October
- New Hieromartyr Sergius Rodakovsky, Archpriest, of Tal, Belorussia (1933) 8 April
- Hieromartyr Sergius Rokhletsov, Protopresbyter, of Veliky Ustyug (1938) 25 April
- New Hieromartyr Sergius Skvortsov, Priest (1943) 12 March
- New Hieromartyr Sergius Stanislavlev, Deacon (1942) 3 November
- New Hieromartyr Sergius Strelnikov, Priest (1937) 26 July
- Saint Sergius the Magistrate, of Paphlagonia, founder of the Nikitiatus Monastery in Nicomedia (866) 28 June
- Venerable Sergius the Obedient of the Kiev Caves Monastery (13th century) 7 October
- Martyr Sergius Tikhomirov, of Moscow (1922) 13 May
- New Hieromartyrs Sergius Uklonsky, Joseph Arkharov, Alexis Uspensky, Priests (1937) 9 September
- New Martyr Sergius Vedernikov (1937) 18 September
- New Hieromartyr Sergius Voskresensky, Priest (1933) 26 February
- New Hieromartyr Sergius Zacharczuk, priest, of Nabroz, Chełm and Podlasie, Poland (1943) 23 April
- New Hieromartyrs Sergius, Archbishop of Eletsk; Nicholas Troitsky, priest; and Martyr Gregory Yurenev (1937) 7 November
- New Hieromartyrs Sergius, Archimandrite, and those with him (1921) 13 August
- Martyr Sergius, by the sword, at Caesarea in Cappadocia (301) 2 January
- New Hieromartyr Sergius, Deacon (1937) 21 December
- Saint Sergius, Pope of Rome (701) West, before the Schism 8 September
- New Hieromartyr Sergius, Priest (1932) 28 February
- Venerable Sergius, Priest and missionary, of Malopinega, Vologda (1585) 16 November
- New Hieromartyr Sergiy Krestnikov (1938) 12 April
- Venerable Seridus, Abbot, of Gaza (ca. 543) 13 August
- Saints Servandus and Germanus, sons of St Marcellus of Léon in Spain, martyred in Cadiz while on their way to Tangiers under arrest (c. 305) West, before the Schism 23 October
- Saint Servatius, Bishop of Tongres, defender against Arianism in the Netherlands (384) West, before the Schism 13 May
- Saint Servulus, a righteous man who was a cripple, used to beg for alms at the door of the church of Saint Clement in Rome, sharing what he received with... (c. 590) West, before the Schism 23 December
- Saint Servus, a layman of noble birth, martyred under the Arian Vandal King Huneric (483) West, before the Schism 7 December
- The Seven Apostolic Men, Martyr Bishops, ordained in Rome by Saints Peter and Paul, and sent to evangelize Spain (1st century) 15 May
- Holy Seven Brothers, early martyrs in Rome: Januarius, Felix, Philip, Sylvanus, Alexander, Vitalis, and Martial, under Antoninus Pius (c. 150) West, before the Schism 10 July
- Seven Hieromartyr Bishops, arrested together with Ecumenical Patriarch Gregory V, subsequently martyred by the Ottoman Turks at the start of the Greek War... (1821) 10 April
- Holy Seven Maccabees 1 August
- The Holy Seven Martyrs of Samosata (297) 29 January
- Seven Virgin-martyrs of Amisus (Samsun) (c. 303-305) 20 March
- The Holy Seven Youths ("Seven Sleepers") of Ephesus 4 August
- The Holy Seven Youths ("Seven Sleepers") of Ephesus (250 and c. 446) 22 October
- Holy seventy (70) martyrs 12 October
- Holy seventy (70) martyrs, with St. Rhipsima (4th century) 30 September
- Saint Severa of Oehren, Abbess of Oehren near Trier in Germany (c. 750) West, before the Schism 20 July
- Saint Severa of St Gemma, Abbess of St Gemma (later Sainte-Sevère) in Villeneuve near Bourges, the sister of St Modoald, Bishop of Trier (c. 680) West, before the Schism 20 July
- Saint Severian (Beridze), deacon, confessor of Adjara (1996) 9 August
- Saints Severian and Aquila, a husband and wife martyred in Julia Caesarea in Mauritania in North Africa West, before the Schism 23 January
- Martyr Severian of Sebaste (320) 9 September
- Hieromartyr Severian, Bishop of Scythopolis in Palestine (452) 21 February
- Saint Severin of Cologne, third known Bishop of Cologne and a prominent opponent of Arianism (c. 403) West, before the Schism 23 October
- Saint Severin, Bishop of Cologne (c. 397) West, before the Schism 8 January
- Saint Severinus Boethius, a Roman senator, consul, magister officiorum, and philosopher, martyred at Pavia in Italy (524) West, before the Schism 23 October
- Saint Severinus of Bordeaux (Seurin), Bishop of Bordeaux in France (c. 420) West, before the Schism 23 October
- Saint Severinus of Noricum, Monk of Göttweig Abbey, Apostle of Austria (Austria and Bavaria) (482) West, before the Schism 8 January
- Saints Severinus of Sanseverino (550) and Victorinus of Camerino (543), brothers who were both bishops and hermits in the 6th century West, before the Schism 8 June
- Saint Severinus of Trier, Bishop of Trier in Germany (c. 300) West, before the Schism 21 December
- Saint Severinus, a Burgundian who became the Abbot of Agaunum in Switzerland (507) West, before the Schism 11 February
- Saint Severinus, a hermit who lived near Paris in France (c. 540) West, before the Schism 27 November
- Saint Severinus, a monk who lived as a hermit in Tivoli in Italy (c. 699) West, before the Schism 1 November
- Martyrs Severinus, Exuperius, and Felician, martyred in Vienne in France under Marcus Aurelius (170) West, before the Schism 19 November
- Saint Severus (Sulpitius I of Bourges, Sulpicius Severus), Bishop of Bourges (591) West, before the Schism 29 January
- Saint Severus and Sixty-Two Companions, martyrs in Syrmium in Pannonia (3rd-4th centuries) West, before the Schism 21 February
- Saint Severus of Avranches, Abbot and Bishop of Avranches (c. 690) West, before the Schism 1 February
- Saint Severus of Catania, Bishop of Catania (c. 812) 24 March
- Saint Severus of Interocrea in Italy (Severus d’Antrodoco), presbyter (6th century) 27 June
- Saint Severus of Naples, Bishop of Naples and wonderworker (409) West, before the Schism 29 April
- Saint Severus of Trier, Bishop of Trier in Germany, Confessor (c. 455) West, before the Schism 15 October
- Saint Severus, a priest from the Abruzzi in Italy (c. 530) West, before the Schism 15 February
- Saint Severus, a priest of noble family, famous for his charity, honoured from time immemorial in the village that bears his name, St Sever de Rustan (c. 500) West, before the Schism 1 August
- Saint Severus, a priest who came from India to enlighten the area around Vienne in France (c. 445) West, before the Schism 8 August
- Saint Severus, Bishop of Barcelona in Spain (633) West, before the Schism 6 November
- Saint Severus, Bishop of Ravenna, attended the Council of Sardica in 344 (348) West, before the Schism 1 February
- Martyr Severus, by the sword 8 September
- Martyrs Severus, Memnon the Centurion, and 38 others, of Thrace () 23 August
- Martyrs Severus, Securus, Januarius and Victorinus, martyrs in North Africa who suffered under the Vandals (c. 450) West, before the Schism 2 December
- Martyr Shalva of Akhaltsikhe, Georgia (1227) 17 June
- Prophet Shemaiah (10th century BC) 8 January
- Prophet Shemaiah (Samaia, Sameas, Semeias), (III Kings 12:22) (10th century BC) 9 January
- Venerable Shio Mgvime of Georgia (6th century) 9 February
- Venerable Shio Mgvime, monk, of Georgia (6th century) 3 March
- Saint Shio of Mgvime, monk, of Georgia (6th century) 9 May
- Saint Sidonius Apollinaris, Bishop of Clermont in France (c. 423-480) West, before the Schism 21 August
- Saint Sidonius of Saint-Saëns, a monk at Jumièges Abbey, later the first abbot of Saint-Säens (c. 690) West, before the Schism 14 November
- Saint Sidronius, a martyr in Rome under Aurelian (c. 270) West, before the Schism 11 July
- Saint Sidwell (Sativola), a Briton from the West of England near Exeter, she was beheaded as a martyr, by a scythe (6th century) West, before the Schism 2 August
- Virgin-martyr Sidwell of Exeter (Sativola) (6th century) West, before the Schism 1 August
- Saint Siffred of Carpentras (Siffrein, Syffroy, Suffredus), a monk at Lérins Abbey and later Bishop of Carpentras in the south of France (c. 540) West, before the Schism 27 November
- Saint Sigeberht of East Anglia (Sigebert), the first Christian King of East Anglia in England (634) West, before the Schism 25 January
- Martyr Sigeberht of East Anglia, King of the East Angles (635) West, before the Schism 16 January, 27 September
- Saint Sigebert III, King of Austrasia (656) West, before the Schism 1 February
- Saint Sigfrid of Sweden, a priest and monk, probably at Glastonbury in England, who went to enlighten Sweden, based in Växjö, and converted King Olaf of Sweden (1045) West, before the Schism 15 February
- Saint Sigfrid, Abbot of Wearmouth (c. 688) West, before the Schism 22 August
- Saint Sigibald, Bishop of Metz in France (c. 740) West, before the Schism 26 October
- Saint Sigiranus (Cyran, Siran, Sigram), abbot and confessor (c. 655) West, before the Schism 5 December
- Saints Sigisbert and Placid, founders of Disentis Abbey (c. 650 or c. 750) West, before the Schism 11 July
- Martyr Sigismund, King of Burgundy (524) West, before the Schism 1 May
- Saint Sigolena of Albi (Segoulème), a nun in the convent of Troclar on the Tarn in the south of France, where she later became abbess (c. 769) West, before the Schism 24 July
- Saint Sigolinus (Sighelm), abbot of Stavelot and Malmédy in Belgium (c. 670) West, before the Schism 29 October
- Saint Sigrada, mother of Sts Leodegarius and Warinus, nun at the convent in Soissons in France (c. 678) West, before the Schism 8 August
- Saints Silas (1783), Paisius and Nathan (1784), monks of Putna Monastery, Moldova 3 May
- Venerable Silas, Bishop of Corinth in Persia (Persidos) 26 November
- Saint Sillan (Silvanus), a disciple of St Comgall in Bangor Abbey, Co. Down, Ireland, and his second successor as abbot there (c. 610) West, before the Schism 28 February
- Venerable Silouan (Silvanus) of the Far Caves in Kiev (13th-14th centuries) 10 June
- Venerable Silouan of the Far Caves in Kiev (13th-14th century) 10 July
- Venerable Silouan the Athonite, Elder, of St. Panteleimon Monastery, Mt. Athos (1938) 11 September
- Venerable Silouan, Elder of St. Panteleimon Monastery, Mount Athos (1938) 24 September
- Venerable Silvanus (Sylvanus) the Ascetic of Gaza, Palestine (before 414) 18 January
- Hieromartyr Silvanus of Gaza, bishop, and with him 40 martyrs (311) 4 May
- Hieromartyr Silvanus of Gaza, Priest, and with him 40 martyrs, by beheading (311) 14 October
- Saint Silvanus of Tabennisi, disciple of Saint Pachomius the Great (in the Thebaid) (4th century) 15 May
- Saint Silvanus, a saint venerated from ancient times in Levroux near Bourges in France West, before the Schism 22 September
- Hieromartyrs Silvanus, Bishop of Emesa, Luke the Deacon, and Mocius the Reader (312) 29 January
- Saint Silvanus, Bishop of Terracina in Italy, Confessor (c. 443) West, before the Schism 10 February
- Hieromartyr Silverius, Pope of Rome (537) West, before the Schism 20 June
- Saint Silverius, Pope of Rome (537) West, before the Schism 2 December
- Saint Silvester 1 March
- Saint Silvester (Sylvester), a companion of St Palladius in enlightening Ireland (c. 420) West, before the Schism 10 March
- Saint Silvester I, Pope of Rome (335) West, before the Schism 31 December
- Saint Silvester of Alexandria, Pope and Patriarch of Alexandria from 1569 to 1590, a period of flourishing 19 February
- Saint Silvester, Bishop of Châlons-sur-Saône in France (c. 525) West, before the Schism 20 November
- Saint Silvester, second Abbot of Moutier-Saint-Jean (Réome) near Dijon in France (c. 625) West, before the Schism 15 April
- Saint Silvinus of Auchy, enlightener of the area near Thérouanne, then a monastic in the Benedictine abbey of Auchy-les-Moines (c. 718) West, before the Schism 17 February
- Saint Silvinus, Bishop of Brescia in Italy (444) West, before the Schism 28 September
- Saint Silvinus, Bishop of Verona in Italy (c. 550) West, before the Schism 12 September
- Saint Simeon (Symeon) I, Patriarch of Antioch (834-840) 16 December
- New Hieromartyrs Simeon Kulgavets and Sergius Lubomudrov, priests (1938) 8 February
- Saint Simeon of Padolirone (Simeon of Mantua), an Armenian hermit who went on pilgrimage to Jerusalem, Rome, Compostella and Tours (1016) West, before the Schism 26 July
- Venerable Simeon Stylites the Elder (459) 1 September
- Saint Simeon Stylites the Younger of Cilicia (597), and his brother George 27 April
- Saint Similien of Nantes (Sambin), third Bishop of Nantes in France, confessor; St Gregory of Tours testified to his holiness (310) West, before the Schism 16 June
- Hieromartyr Simitrius priest, and 22 other martyrs, who suffered under Antoninus Pius, at Rome (159) West, before the Schism 26 May
- New Hieromartyrs Simo Banjac and Milan Stojisavljevic, and the latter’s son Martyr Milan of Glamoc, Serbia (1941-1945) 21 July
- New Hieromartyr Simon (Shleyev), Bishop of Ufa (1921) 5 August
- Monk-martyr Simon (Symeon), founder of Volomsk Monastery, Vologda (1641) 12 July
- Saint Simon of Vladimir and Suzdal, Kiev Caves, Bishop (1226) 10 May
- Blessed Simon of Yurievets and Zharki, Fool-for-Christ (1584) 10 May, 4 November
- Saint Simon the Myrrhgusher, founder of Simonopetra, Mount Athos (1287) 28 December
- Saint Simon the Zealot, Apostle (1st century) 10 May
- Venerable Simon, Abbot of Soiga Monastery, Vologda (1562) 24 November
- Saint Simon, Bishop of Suzdal (c. early 12th century) 23 May
- Saint Simon, Metropolitan of Moscow (1511) 30 April
- Venerable Simon, Wonderworker of Calabria (10th century) 19 November
- Saint Simpert (Simbert, Sinthert), Bishop of Augsburg in Germany (c. 809) West, before the Schism 13 October
- Saint Simplician, a friend and advisor of St Ambrose, whom he succeeded as Bishop of Milan (400) West, before the Schism 16 August
- Saint Simplicius of Autun, a married man who lived a virginal life with his wife and became Bishop of Autun (c. 360) West, before the Schism 24 June
- Saint Simplicius of Bourges, Bishop of Bourges in France, he defended the Church against the Arian Visigoths (477) West, before the Schism 16 June
- Martyr Simplicius of Olbia, Bishop, in Sardinia (c. 284–305) West, before the Schism 15 May
- Saint Simplicius of Verona, Bishop of Verona in Italy (c. 535) West, before the Schism 20 November
- Saint Simplicius, a disciple of St Benedict and third Abbot of Montecassino (c. 570) West, before the Schism 22 October
- Saints Simplicius, Faustinus and Beatrix, two brothers and their sister martyred in Rome under Diocletian (c. 303) West, before the Schism 29 July
- Saint Simplicius, Pope of Rome (468-483), who upheld the decisions of the Council of Chalcedon against Monophysitism, and dealt with the Arian King Odoacer... West, before the Schism 10 March
- Venerable Sinaites of Serbia (from Ravanica) (14th century) 6 May, 19 May
- Saint Sincheall, a disciple of St Patrick and founder of the monastery of Killeigh in Offaly, where there were 150 monks (5th century) West, before the Schism 26 March
- Saint Sindulf of Rheims, a hermit in Aussonce near Rheims in France, Confessor (660) West, before the Schism 20 October
- Saint Sindulf of Vienne (Sindulphus), the thirty-first Bishop of Vienne in France (c. 669) West, before the Schism 10 December
- Saint Sinnell of Cleenish (Senilis), Ireland (6th century) West, before the Schism 12 November
- Saint Siricius, Pope of Rome (399) West, before the Schism 26 November
- Martyr Sisenandus Córdoba, a Deacon in the church of St Acisclus in Córdoba in Spain, beheaded under Abderrahman II (851) West, before the Schism 16 July
- Saint Sisinius the Confessor, Bishop of Cyzicus (c. 325) 23 November
- Hieromartyr Sisinius, by the sword 22 November
- Martyrs Sisinius, Martyrius, and Alexander, near Trent, in the time of Emperor Honorius (397) West, before the Schism 29 May
- Saint Sisinnios, 'Bishop of God', in the region of the Metropolis of Ephesus (c. 919-944) 12 February
- Venerable Sisoes of the Kiev Caves (13th century) 24 October
- Venerable Sisoes of the Kiev Caves, Schemamonk of the Kiev Caves (13th century) 6 July
- Venerable Sisoës the Great of Egypt (429) 6 July
- Saint Sithney (Sezni), patron saint of Sithney, Cornwall (c. 529) West, before the Schism 4 August
- Saint Siviard, monk at Saint-Calais on the River Anisole in France, who succeeded his father as abbot of the monastery (729) West, before the Schism 1 March
- The Holy Six "Allemagne Saints", in Cyprus (12th century) 6 October
- The Holy Six Martyrs 4 January
- Holy Six Martyrs, by the sword (298) 21 September
- Saint Sixtus I (Xystus), Pope of Rome from 117 to c 125, sometimes referred to as a martyr (c. 125) West, before the Schism 3 April
- Hieromartyr Sixtus II (Xystus), Pope of Rome, martyred with his deacons [Felicissim and Agapit] (258) West, before the Schism 7 August
- Saint Sixtus III (Xystus), Pope of Rome from 432 (440) West, before the Schism 28 March
- Saint Sixtus III, bishop of Rome (440) West, before the Schism 19 August
- Saint Sixtus of Reims, first Bishop of Rheims in France (c. 300) West, before the Schism 1 September
- Saint Skiota of Georgia (c. 13th century) 25 May
- New Martyrs slain at Raithu Monastery near Kazan: Joseph, Anthony, Barlaam, Job, and Sergius, Hieromonks, and Peter, Novice (1930) 14 January
- Saint Slebhene (Sléibíne mac Congaile), a monk from Ireland, he became Abbot of Iona in Scotland (767) West, before the Schism 2 March
- Saint Smaragda Onishchenko of Nizhyn (1945) 10 January
- Saint Snandulia of Persia (380) 3 November
- Saints Socrates and Stephen, by tradition early martyrs venerated in Britain, now England West, before the Schism 17 September
- Hieromartyr Socrates, Priest, and Martyr Theodote, of Ancyra (c. 230) 21 October
- Venerable Confessor Sofian (Boghiu) of Antim (2002) 16 September
- Saint Sola (Sol, Solus, Suolo), Anglo-Saxon missionary priest under Saint Boniface, Germany (794) West, before the Schism 3 December
- Virgin-martyr Solangia (Solange) (880) West, before the Schism 10 May
- Saint Solemnis (Soleine, Solen), Bishop of Chartres (511) West, before the Schism 25 September
- Saint Solina, born in Gascony in France, she escaped to Chartres to avoid marriage to a pagan, was beheaded in Chartres (c. 290) West, before the Schism 17 October
- Martyrs Solochon, Pamphamer, and Pamphalon, soldiers, at Chalcedon (c. 286-305) 17 May
- Saint Solomon III, King of Brittany, a brave warrior against Franks and Northmen alike, martyr (874) West, before the Schism 25 June
- Saint Solomon, Archbishop of Ephesus 2 December
- Virgin-martyr Sophia (1938) 15 February
- Venerable Sophia (Solomonia) Saburova of Suzdal, the Wonderworker, Nun, wife of Grand Duke Basil III of Moscow (1542) 16 December
- Martyrs Sophia and her three daughters Faith (Vera), Hope (Nadezhda), and Love (Lyubov), at Rome (c. 137) 17 September
- Martyrs Sophia and Irene, of Egypt, by the sword (3rd century) 18 September
- Venerable Sophia of Ainos, Thrace, Mother of Orphans (10th-11th centuries) 4 June
- Martyr Sophia of Fermo (c. 250) West, before the Schism 30 April
- Blessed Sophia of Kleisoura (Myrtidiotissa in Schema), the ascetic of Kleisoura, Fool-for-Christ (1974) 23 April, 6 May
- Saint Sophia of Slutsk and Minsk, descendant of the Sovereigns of the Kyivan-Rus' (1612) 19 March
- Martyr Sophia the Healer, a physician, by beheading 22 May
- Saint Sophia the Wonderworker 18 December
- Saint Sophia, first Abbess of Shamordino Convent (1888) 24 January
- Martyr Sophia, mother of the virgin-martyrs Faith, Hope and Charity, at Rome (c. 173) West, before the Schism 30 September
- Venerable Sophronios, Bishop 19 February
- Saint Sophronius (Smirnov), Archimandrite, of Svyatogorsk Monastery (1921) 19 July
- Venerable Sophronius I, Bishop of Cyprus (6th century) 8 December
- Venerable Sophronius of Bulgaria, Monk (1510) 28 May
- Venerable Sophronius of Jerusalem, Patriarch of Jerusalem (638) 11 March
- Venerable Sophronius of St. Anne's skete on Mount Athos (18th century) 18 August
- Saint Sophronius of the Kiev Caves, recluse (13th century) 11 May
- Saint Sophronius of Vratsa, Bishop of Vratsa, Bulgaria (1813) 11 March
- Saint Sophronius the Archbishop of Cyprus (6th century) 9 December
- Saint Sophronius, Abbot of the Monastery of St. Theodosius, in Palestine (542) 21 March
- Saint Sophronius, Bishop of Achtaleia in Iberia (Georgia) (1803) 8 September
- Saint Sophronius, Bishop of Irkutsk (1771) 30 March
- Saint Sophronius, recluse of the Kiev Caves (13th century) 11 March
- Martyr Sositheus of Persia, by the sword (553) 9 December
- Martyrs Sossios and Theokleios (c. 286–305) 24 December
- Holy Apostles Sosthenes, Apollos, Cephas, Caesar, and Epaphroditus, of the Seventy (1st century) 30 March
- Saints Sostratus, Spirus, Eraclius, Eperentius and Cecilia, martyrs of Syrmium in Pannonia (4th century) West, before the Schism 8 July
- Hieromartyr Soter, Pope of Rome (c. 174) West, before the Schism 22 April
- Saint Soteris, virgin-martyr in Rome under Diocletian (304) West, before the Schism 10 February
- Saint Sozomen (Sozomenos, Sozomonos), Bishop of Karpaseia in Cyprus, and Wonderworker (12th century) 20 November
- Venerable Sozomenos, Bishop of Karpaseia in Cyprus, and Wonderworker (12th century) 21 November
- Martyr Sozon of Cilicia (304) 7 September
- Martyr Sozon of Cyprus (7th century) 7 September
- Saint Sozon of Nicomedia 7 August
- Saint Speciosus, a monk at Terracina in Italy (c. 555) West, before the Schism 15 March
- Saint Spes (Speus), an Abbot of Campi in central Italy (ca. 513) West, before the Schism 28 March
- Martyrs Speusippus, Eleusippus, and Melapsippus, Cappadocian triplets, and their grandmother Leonilla, and with them Neon, Turbo, and Jonilla (Jovilla), in... (c. 161-180) 16 January
- Saint Spinulus (Spinula, Spin), a monk at Moyenmoutier with St Hidulf, later founder of the monastery of Bégon-Celle (now Saint-Blasien) (707 or 720) West, before the Schism 5 November
- Venerable Spyridon and Nicodemus the Prosphora-bakers, of the Kiev Caves (1148) 31 October
- Saint Spyridon the Wonderworker, Bishop of Tremithus (348) 12 December
- Saint Spyridon, Serbian Patriarch (1389) 15 June
- Saint Stachys, Bishop of Hierapolis (in Phrygia) (1st century) 14 November
- Martyr Stacteus, in Rome West, before the Schism 28 September
- New Martyrs Stamatius and John, brothers, and their companion Nicholas, of Spetses, at Chios (1822) 3 February
- New Martyr Stamatius of Demetrias, near Volos, at Constantinople (1680) 16 August
- New Hieromartyr Stanislav Nasadil, victim of the Nazi Croatia concentration camp at Gospić (1941) 20 June
- New Martyr Stanko the Shepherd, of Montenegro (1712) 29 April
- Blessed Stefan Lazarević, King of Serbia (1427) 9 October
- New Hieromartyrs Stephan Kostogryz and Alexander Aksenov, Priests (1937) 13 September
- Saint Stephen "the New Light" of Constantinople (912) 9 December
- New Hieromartyr Stephen (Bekh), Bishop of Izhevsk (1933) 13 March, 13 April
- New Hieromartyr Stephen (Kreidich), Priest, of Robchik, Bryansk (1937) 7 September
- New Hieromartyr Stephen (Kuskov), Hieromonk, of Nikolskoye, Tver (1937) 4 September
- Saints Stephen and Anthimus of Constantinople, Priests, of the Fervent Ones ("the Ever-Vigilant") (5th century) 7 June
- Martyrs Stephen and Peter of Kazan (1552) 24 March
- New Hieromartyr Stephen Chitrov, Priest (1918) 5 August
- Saint Stephen Dragutin of Serbia (monk Theoctistus Dragutin) (1316) 12 March
- New Hieromartyr Stephen Ermolin, Priest (1937) 2 September
- Martyrs Stephen Frantov and Nicholas Nekrasov (1938) 22 February
- New Hieromartyr Stephen Grachev, Priest (1938) 25 January
- Saint Stephen I of Hungary, King of Hungary (1038) 20 August
- Saint Stephen II of Constantinople, Patriarch of Constantinople (928) 18 July
- Hieromartyr Stephen II, Patriarch of Antioch (479) 25 April
- Saint Stephen Milutin, King of Serbia (1320), his brother St. Dragutin (monk Theoctistus) (1316), and their mother St. Helen (1306) 30 October
- Saint Stephen of Apt, Bishop of Apt in the south of France in 1010 (1046) West, before the Schism 6 November
- Saint Stephen of Cajazzo, Abbot of San Salvatore Maggiore, and Bishop of Cajazzo (1023) West, before the Schism 29 October
- Saint Stephen of Cardeña and Companions, Abbot of the Castilian monastery of Cardeña near Burgos in Spain, where there were over two hundred monks, martyred... (872) West, before the Schism 6 August
- Saint Stephen of Hungary, king (1038) 7 August
- Saint Stephen of Hungary, King of Hungary (1038) West, before the Schism 16 August
- Venerable Stephen of Komel, founder of Ozersk Monastery in Vologda (1542) 12 June
- Saint Stephen of Lyon, Bishop of Lyon in France, he was active in converting the Arian Burgundians to Orthodoxy, Confessor (512) West, before the Schism 13 February
- Saint Stephen of Makhrishche, founder of Makhrishche Monastery in Vologda (1406) 14 July
- Venerable Stephen of Mar Sabbas monastery in Palestine, hymnographer (807) 28 October
- Saint Stephen of Omsk (1877) 30 June
- Saint Stephen of Perm, Bishop of Perm (1396) 26 April
- Saint Stephen of Perugia, third Abbot of St Peter in Perugia in Italy (1026) West, before the Schism 16 September
- Saint Stephen of Placidian near Constantinople 11 January
- Hieromartyr Stephen of Rhegium (Stephen of Nicea), Bishop of Rhegium, disciple of Apostle Paul, and with him Bishop Suerus and the women Agnes, Felicitas... (1st century) West, before the Schism 5 July
- Saint Stephen of Rieti, an Abbot in Rieti in Italy whom St Gregory the Great describes as 'rude of speech but of cultured life' (c. 590) West, before the Schism 13 February
- New Martyr Stephen Pimenovich Nalivayko (1945) 30 January
- New Hieromartyr Stephen Ponomarev, Protopresbyter, at Alma-Ata (1933) 5 January
- Saint Stephen Stiljanovic, despot of Srem, Serbia (1540), and his wife St. Elena (Elizabeth in monasticism) (c. 1543) 4 October
- Saint Stephen the Blind, King of Serbia (1468) 9 October
- Venerable Stephen the Confessor and Wonderworker, Abbot of Tryglia (815) 26 March
- Saint Stephen the Confessor and Wonderworker, Abbot of Tryglia (815) 28 March
- Saint Stephen the Confessor, Archbishop of Surozh in the Crimea (c. 790) 15 December
- Saints Stephen the First-Crowned (in monasticism Simon) (1224), David (13th century), and Stephen Vladislav (after 1264), of Serbia 24 September
- Venerable Monk-martyr and Confessor Stephen the New of Mt. St. Auxentius (767) 28 November
- Saint Stephen the New, Patriarch of Constantinople (893) 17 May
- Venerable Stephen the Sabaite (Stephen the Hymnographer) (794 or 807) 13 July
- Venerable Stephen the Wonderworker 28 December
- Venerable Stephen the Wonderworker, ascetic 31 March
- Venerable Stephen the Wonderworker, in Ascalon, Palestine (778) 2 April
- Saint Stephen Vladislav of Serbia (1243) 30 July
- Great-martyr Stephen-Urosh III of Decani (1331) 11 November
- Saint Stephen-Urosh V, King of Serbia (1371), and his mother Saint Helena of Bulgaria, Empress of Serbia (1376) 2 December
- Venerable Stephen, Abbot of Chenolakkos Monastery in Triglia, near Chalcedon (716) 14 January
- Saint Stephen, Abbot of Piperi Monastery in Serbia (1697) 20 May
- Martyrs Stephen, Barnabas, Trophimus, Dorymedon, Cosmas, Damian, Sabbas, Bassa, Abramios, and others with them 31 October
- Saint Stephen, Elder, of Vyatka (1890) 15 August
- Martyrs Stephen, Mark, and Mark at Antioch in Pisidia, by beheading (290) 22 November
- Saint Stephen, monk, of Constantinople (614) 27 February
- Hieromartyr Stephen, Pope of Rome, and Companions (257) 2 August, 3 August, 7 September
- New Hieromartyr Stephen, Priest (1918) 16 August
- Martyr Straton of Nicomedia (3rd century) 13 September
- Martyrs Straton, Philip, Eutychian, and Cyprian, of Nicomedia (303) 17 August
- Martyr Stratonicus, by the sword 30 September
- Blessed Studius, founder of the Studion Monastery (5th century) 20 June
- Saint Sturm (Sturmius), Abbot and Apostle of Saxony, founder of Fulda Monastery, Germany (779) West, before the Schism 17 December
- Venerable Stylianos of Paphlagonia, monk (6th century) 26 November
- Martyr Styracius, by the sword 8 August
- Saint Suairlech, first Bishop of Fore in Westmeath, Ireland, from c. 735-750 (c. 750) West, before the Schism 27 March
- Saint Suitbert (Swithbert), "Apostle of the Frisians", monastic founder in the Netherlands (713) West, before the Schism 1 March
- Martyr Sukia (Suchias) and nineteen companions with him (c. 100-130) 15 April
- Saint Sulien (Sulian, Silin), born in Brittany, he founded a small monastery in Luxulyan in Cornwall (6th century) West, before the Schism 29 July
- Martyrs Sulpicius and Servilian, martyrs in Rome who were beheaded under Trajan (c. 117) West, before the Schism 20 April
- Saint Sulpicius II (Sulpitius II) the Pious (Severus the Pious), Bishop of Bourges (644, 646, or 647) West, before the Schism 17 January
- Saint Sulpicius of Bayeux (Sulpice), Bishop of Bayeux in France from c 838 to 843, martyred by the Vikings in Livry West, before the Schism 4 September
- Virgin-martyr Sunniva (Sunnifa) and companions, on Selje Island, Norway (10th century) West, before the Schism 8 July
- Saint Suranus, Abbot of a monastery at Sora near Caserta, martyred by the Lombards (c. 580) West, before the Schism 24 January
- Virgin-martyr Susanna and those with her (295) 11 August
- Martyr Susanna the Deaconess, Joanna in monasticism, of Palestine (4th century) 15 December
- Right-Believing Sviatoslav II Yaroslavich, Grand Prince of Kiev, son of Saint Yaroslav the Wise (1076) 21 May
- Saint Sviatoslav-Gabriel and his son Saint Dimitry, of Yuriev (1253) 3 February
- Saint Swithbert the Younger, Bishop of Werden in Westphalia (807) West, before the Schism 30 April
- Saint Swithun, Bishop and Wonderworker of Winchester (862) West, before the Schism 2 July
- Saint Syagrius (Siacre) of Nice, a monk at Lérins Abbey, who later founded the monastery of St Pons, at Cimiez, then becoming Bishop of Nice 777-787 West, before the Schism 23 May
- Saint Syagrius (Siacre), Bishop of Autun and Confessor (600) West, before the Schism 27 August
- Saint Sylvester I, Pope of Rome (335) 2 January
- Saint Sylvester of Obnorsk, Abbot of Obnora Monastery (1379) 25 April
- New Hieromartyr Sylvester Olshevsky, Archbishop of Omsk and Pavlodar (1920) 25 February
- Venerable Sylvester the Wonderworker of the Kiev Near Caves (12th century) 2 January
- Saint Sylvia, mother of St. Gregory the Dialogist (6th century) 4 November
- Saint Sylvia, the mother of St Gregory the Great (c. 572) West, before the Schism 3 November
- Saint Sylvius of Toulouse, Bishop of Lyon (c. 400) West, before the Schism 31 May
- Venerable Symeon "the Ancient" of Mount Sinai (c. 390) 26 January
- Saints Symeon (1476) and Amphilochius (1570), of Pângărați Monastery, Romania 7 September
- Saint Symeon (Popović), Archimandrite of Dajbabe Monastery, Montenegro (1941) 19 March
- Hieromartyr Symeon (Shemon Bar Sabbae), Bishop in Persia, and those with him (341) 17 April
- Saints Symeon (Stefan) (1656), Elias (Iorest) (1678) and Sava (Brancovici) (1683), Metropolitans of Ardeal, Transylvania, Confessors against the Calvinists 24 April
- New Hieromartyr Symeon Konyukhov, Priest (1918) 15 October
- Venerable Symeon Metaphrastes ('the Translator') of Constantinople (960) 9 November
- Venerable Symeon of Emesa, Fool-for-Christ (590) 23 July
- Venerable Symeon of Emesa, Fool-for-Christ (590), and his fellow ascetic St. John (c. 590) 21 July
- Saint Symeon of Novgorod, Archbishop of Novgorod (1421) 15 June
- Venerable Symeon of Sinai (5th century) 25 June
- Saint Symeon of Syracuse (or of Mount Sinai or Trier) (1035) 1 May
- Venerable Symeon of the Pskov-Caves Monastery, Hieroschemamonk (1960) 5 January
- Saint Symeon of Thessaloniki, Archbishop of Thessaloniki (1429) 15 September
- New Martyr Symeon of Trebizond, at Constantinople (1653) 14 August
- Saint Symeon of Tver, Bishop of Polotsk and Tver, first bishop there (1289) 3 February
- Saint Symeon Stylites (the Younger) of Sicily (6th century) 27 July
- Saint Symeon Stylites of Lesbos (c. 845) 1 September
- Venerable Symeon Stylites the Younger of the Wonderful Mountain (c. 596) 24 May
- Venerable Symeon the Archimandrite and Stylite 26 July
- Venerable Symeon the Barefoot, of Philotheou Monastery, Mount Athos (1594) 19 April
- Holy and Righteous Symeon the God-receiver and Anna the Prophetess (1st century) 3 February
- Saint Symeon the Kinsman of the Lord, Apostle of the Seventy and Hieromartyr (107) 27 April
- Venerable Symeon the Myrrh-gusher (Stefan Nemanja), Grand Prince of Serbia (1200) 13 February
- Venerable Symeon the New Theologian (1022) 12 October
- Venerable Saints Symeon the New Theologian (1022), and his elder, Symeon the Studite (Symeon the Reverent, the Pious), of the Studion (987) 12 March
- Venerable Symeon the Newly-Revealed (born 1042) 24 July
- Saint Symeon the Stylite (the third stylite), of Cilicia (6th century) 3 July
- Martyr Symeon Turkin (1937) 10 September
- Saint Symeon, Abbot and Wonderworker of Gareji (1773) 4 September
- New Hieromartyr Symeon, Bishop of Samokovo, Bulgaria (1737) 21 August
- Martyrs Symeon, Isaac, and Bachtisius of Persia (339) 18 May
- Venerable Symeon, Metropolitan of Smolensk (1699) 4 January
- Saint Symmachus, Pope of Rome (514) West, before the Schism 19 July
- Saint Symphorian of Autun, martyred for refusing to sacrifice to a pagan goddess (2nd century) West, before the Schism 22 August
- Martyr Symphorosa of Tivoli near Rome, and her seven martyred sons (c. 138) West, before the Schism 18 July
- Saints Symphronius, Olympius, Theodulus and Exuperia, all burnt to death under Valerian (257) West, before the Schism 26 July
- Venerable Syncletica (Synkletika, Syncletike), Nun of Alexandria (c. 350 or c. 460) 5 January
- Saints Syncrotas, Antigonus, Rutilus, Libius, Senerotas and Rogatianus, martyrs at Sirmium in Pannonia (4th century) West, before the Schism 23 February
- Martyr Synesius (Synetus) of Rome, a Reader, tortured and beheaded for refusing to sacrifice to idols (270-275) West, before the Schism 12 December
- Martyr Synesius (Synetus), by the sword 22 February
- Saint Synesius of Irkutsk (1787) 10 May
- Saint Synesius, ascetic of Lysos, Cyprus 1 March
- Saint Synesius, Bishop of Karpasia (Carpasia) on Cyprus (c. 5th century) 23 May
- Saint Synesius, Bishop of Karpasia in Cyprus, Wonderworker (c. 5th century) 26 May
- Venerable Syra (Syria), by tradition, the sister of St Fiacre (Fiaker), an anchoress in France (7th century) West, before the Schism 8 June
- Saint Syra, a nun at Faremoutiers Abbey, from where she was asked by Bishop Ragnebaud to become Abbess of Châlons-sur-Marne (c. 660) West, before the Schism 23 October
- The Holy Syrian Martyrs (4th century) 11 March
- Saint Syrus of Genoa, priest and later Bishop of Genoa in Italy from c. 324 to c. 380, he is the main patron of the city West, before the Schism 29 June
- Saint Syrus, first Bishop and main patron-saint of Pavia in Italy (c. 1st century) West, before the Schism 9 December